Structural Research Lab 700 MHz NMR Spectrometer

Methodology of NMR: - experiments of high dimensionality for demanding cases of crowded spectra (e.g. for disordered proteins) - experiments based on non-uniform sampling - new experimental techniques for small organic molecules and macromolecules of biological interest, measurements of earlier inaccessible parameters, improvement of precision and accuracy, new methods for acquisition multidimensional spectra, with better resolution in shorter time . - Structural studies of biomolecules - Application of modern NMR techniques for chiral recognition. - Studies of host-guest complexes, for example with cyclodextrines. - Application of residual dipolar couplings and quadrupolar interactions in weakly oriented media in structural studies of organic molecules. - Investigations of origin of natural compounds using 2H NMR. - Studies of powder samples in the high magnetic field: identification of polymorphs, determination of chemical shift tensor, structural studies.